Selank
A peptide with anxiolytic potential, Selank is explored for helping maintain calm focus and stress resilience.
Laboratory and educational research purposes only.What is Selank?
Selank is a synthetic heptapeptide developed as an analog of tuftsin (an immune-modulating peptide). It is classified as both a nootropic and an anxiolytic peptide, with additional roles in immune regulation. It has been studied in Russia for the treatment of anxiety, depression, stress, and cognitive decline.
Mechanism(s) of Action
GABAergic pathway modulation → enhances inhibitory signaling, reducing anxiety and stress.
BDNF/TrkB pathway activation → increases brain-derived neurotrophic factor, improving neuroplasticity and learning.
Serotonergic and dopaminergic regulation → stabilizes mood and motivation.
Immune modulation pathways → regulates cytokine balance, improving immune system resilience.
1. Reduces anxiety — GABAergic modulation produces calming effects without sedation or addiction risk.
2. Improves cognition — enhances memory, focus, and mental clarity.
3. Supports mood — stabilizes serotonin and dopamine balance, potentially reducing depression symptoms.
4. Neuroprotective — protects neurons from oxidative stress and excitotoxic damage.
5. Immune balance — modulates cytokine release and improves immune regulation.
6. Stress resilience — enhances adaptability to physical and emotional stress.
7. Potential antidepressant effects — via serotonergic and dopaminergic modulation.
Summary:
Selank is a nootropic and anxiolytic peptide that improves anxiety, cognition, mood, and immune regulation. Its main pathways include GABAergic, BDNF/TrkB, and serotonin/dopamine systems, making it a versatile peptide for mental health and stress resilience with minimal side effects.
