HCG 5000 iu
In research settings HCG is evaluated for its role in supporting natural hormone production and metabolic balance.
Laboratory and educational research purposes only.What is HCG (Human Chorionic Gonadotropin)?
HCG is a naturally occurring glycoprotein hormone produced by the placenta during pregnancy. In medicine, it is used for fertility treatments, hormone regulation, and testosterone support. Structurally similar to LH (luteinizing hormone), it mimics LH activity at the gonads.
Mechanism(s) of Action
LH receptor pathway (cAMP/PKA signaling): hCG binds to LH receptors on Leydig cells in testes → stimulates testosterone production.
Ovarian follicle stimulation: Promotes progesterone and estrogen production, aiding ovulation.
Steroidogenesis pathway activation: Enhances synthesis of sex hormones from cholesterol.
Influences the hypothalamic–pituitary–gonadal (HPG) axis by mimicking LH.
1. Male fertility & testosterone support — increases intratesticular testosterone and sperm production.
2. Restores testicular function during TRT — prevents testicular shrinkage and maintains fertility in men on testosterone therapy.
3. Female fertility — used to trigger ovulation and support luteal phase in assisted reproductive technology (ART).
4. Supports pregnancy — maintains corpus luteum and progesterone secretion in early pregnancy.
5. Pubertal induction — used in boys with delayed puberty due to hypogonadism.
6. Muscle preservation in calorie deficit — sometimes used off-label in weight loss regimens (though controversial).
7. May improve mood and energy in men with secondary hypogonadism by restoring testosterone.
Summary:
HCG is primarily used for fertility and hormone regulation, mimicking LH to stimulate testosterone in men and ovulation/progesterone in women. It’s especially valuable in men on TRT who want to preserve fertility and testicular size.